Molecular dance: A protein called Necdin plays a role in SYNGAP1 deficiency syndromes such as Prader-Willi syndrome, according to a new study. Investigators show that Necdin helps stabilize SYNGAP protein, and depletion of Necdin in mice leads to decreased levels of SYNGAP protein, reduced sociability and morphological changes in prefrontal cortex neurons. The paper adds […]
