Parallel tracks: Two distinct targets of anterior cingulate cortical neurons—the zona incerta and the limbic sector of the thalamic reticular nucleus—contribute to a pair of effects observed in a mouse model of autism: sociability and attention, respectively, according to a new paper. Mice carrying SHANK3b variants showed altered social behavior and attentional control, which could […]
Many genes linked to autism disrupt the same developmental pathways during embryonic development and the first two weeks of life, according to a new study in mice. As the animals mature, those shared changes give way to more gene-specific phenotypes, suggesting that the underlying pathways shift over time. Different autism mouse models showed similar developmental […]
