Imbalanced Characteristics: Animals with mutated ADNP have motor difficulties that are more pronounced in female mice. Photography by Rick Dahms Mice with a mutation in an autism-related gene called ADNP show gender-specific changes in gene expression, behavior, and other traits, a new study shows. The mice can mimic some of the traits seen in humans […]
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Social Studies: Mice in the autism model have atypical social behavior, possibly due to the way their brain processes the feeling of “self”. Photo by Rick Dahms A mutation in a gene associated with autism disrupts the brain’s ability to differentiate between itself and others, according to a new study in mice. Correcting the mutation […]
Disorganized scaffolds: Immature brain cells from mutant CUL3 mice have a disordered cytoskeleton (right) compared to controls (left). Mutations in CUL3, a leading autism gene, can disrupt the movement of neurons during development and disrupt the precise assembly of the brain, suggests a new study. Correcting this misdirection could lead to therapy for autism in […]