Cell save: Deleting one copy of TSC1 in only Purkinje cells (red) reduces activity in those cells and alters social behavior in mice; a brief treatment with rapamycin seems to block these effects.Courtesy of Peter Tsai Briefly suppressing an overactive signaling pathway in juvenile mice that have an autism-linked mutation blocks them from developing some […]
Ashley de Marchena Assistant Professor, University of Sciences Casey Zampella scientist, Center for Autism Research, Philadelphia Children’s Hospital Eating a delicious meal, scolding a friend, playing an instrument, tackling bouldering in the middle of your favorite hike – some of life’s greatest joys depend on diverse and complex motor skills. Despite the central importance of […]
