Subdued response: Organoids with microglia (bottom) show a lower interferon response (red) than organoids without microglia (top), suggesting that these immune cells help reduce cell stress. Adding non-neural brain cells called microglia to cortical organoids speeds up the rate of maturation of their neurons, increases the synchronization of their firing, and appears to reduce cellular […]
Brain Boost: Electrical stimulation of the fornix weakened abnormal inhibitory signals in mice with CDKL5 mutations and restored their performance in learning and memory tasks. Manjurul / iStock Chronic electrical stimulation of the fornix, a bundle of nerve fibers deep in the brain, saves learning and memory deficits in mice with mutations in the autism-linked […]
