By compensating for a missing copy of SCN2A, one of the genes most strongly linked to autism, a variant of the gene-editing technology CRISPR can reduce susceptibility to seizures, according to a new study in mice. SCN2A haploinsufficiency—in which gene variants cause someone to have just one functional copy of SCN2A instead of the usual […]
PLOS Data: According to the guidelines of the PLOS journals, researchers must make all data necessary to replicate their study results publicly available upon publication. Last month, PLOS ONE magazine added an editorial “word of concern” to a study of brain imaging of autism published seven years ago after a dispute over access to the […]
Mapping of neurons: BARseq2 can track neuronal pathways and at the same time measure gene expression within cells. In this mouse brain slice, each point represents the location of a unique mRNA molecule and each color represents a different gene. Courtesy of Xiaoyin Chen A new method can map the pathways of thousands of neurons […]
How do you think your child would react if you asked them to pour a gallon of paint over you? I bet they would react just like my child: with a sly smile. My youngest son loved the idea of doing something with his mother that allowed him to be a little bit creative, a […]
