Posts Tagged
‘excitatory’

August 26, 2025

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by: admin

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Tags: Altered, CHD8deficient, circuits, excitatory, mice

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Categories: autism

Upstream movers: Mice deficient in the autism-linked gene CHD8 have altered structure and function of excitatory neurons, synapses and circuits, according to a new study. The animals developed atypically large heads, consistent with a similar effect observed in humans with CHD8 variants. But this macroencephaly was not accompanied by more or bigger neurons. Still, glutamate-containing […]