If repeated: Deletions of ASH1L cause excessive grooming in mice, which treatment with the cancer drug vorinostat is alleviated. Mark Bowler / Science Source A cancer drug that boosts gene expression reduces repetitive behaviors and improves memory and sociability in a mouse model of autism, according to a new study. However, the treatment did not […]
My oh myelin: In a new mouse model of autism, the males have an unusually thick myelin in the cerebellum, which correlates with more intense autism-like features. Male mice exposed to atypically low levels of a placental hormone in the womb have altered brain development and anti-social behavior, according to a new study. The results […]
Protective function: PTEN pups from wild-type mice (left) have more neurons (brown) than those from PTEN mothers (right). Women who are genetically predisposed to inflammation may be more likely to have children with characteristics of autism, according to a new study in mice. Previous work suggests that inflammation in a pregnant woman – due to […]
Seeing stars: Mice that were exposed to an immune response before birth have high levels of inflammatory molecules in their astrocytes. Pregnant mice that have been treated to build an immune response have pups that display autism-like behavior and altered immune cells, according to a new study. Injecting immune cells from other mice into adult […]
