Further information counsel adjustments in diagnostics underlie will increase in autism diagnoses, and extra
Loose links: Associations between various early-life factors and later-life diagnoses of autism or attention-deficit/hyperactivity disorder appear to be weakening, according to a new study. Children diagnosed with either condition differ from children without these conditions on such factors as birth weight and household income. But an analysis of records from a Danish registry revealed that these differences diminished over the decade studied: 2012 to 2022. The findings suggest that the increase in autism and ADHD prevalence reflect changes in diagnostic practices and specialized health services.
Autism research spotted this week:
- “Long-read proteogenomic atlas of human neuronal differentiation reveals isoform diversity informing neurodevelopmental risk mechanisms” Nature Communications
- “De novo structural variants in autism spectrum disorder disrupt distal regulatory interactions of neuronal genes” Genome Research
- “Autism-risk gene mutations convergently disrupt sexually dimorphic oxytocin circuits to lower social engagement” bioRxiv
- “Clinical deep sequencing to diagnose pathogenic mosaic variants in malformations of cortical development and epilepsy” medRxiv
See also: “Patchwork mutations present a new frontier for autism research”
